Sample-to-result detection of Influenza A and B viral RNA in 20 minutes

The Liat™ Influenza A/B Assay is currently the only test that has equivalent or better sensitivity and specificity as lab-based nucleic acid tests, while substantially matching the time-to-result and ease-of-use of rapid immunoassays.

The Problem:
Influenza is a highly contagious acute respiratory illness that affects between 5% and 20% of the U.S. population each year, leading to more than 200,000 hospitalizations and as many as 49,000 deaths, according to the U.S. Centers for Disease Control and Prevention (CDC)¹. Influenza A, including subtypes A/2009 H1N1 and H3N2, and influenza B, are considered to be the predominant seasonal influenza viruses.

A World Health Organization (WHO) study showed that rapid influenza immunoassays have a sensitivity of only 10-70%². On the other hand, conventional nucleic acid tests have a turnaround time of hours to days, which makes it difficult to manage patients presenting with influenza-like illness.

The Solution:
The Liat Influenza A/B Assay is an automated multiplex real-time RT-PCR assay for the rapid in vitro qualitative detection and discrimination of influenza A and influenza B virus RNA in nasopharyngeal swab specimens.

		Fastest. Having a turnaround time of only 20 minutes, the Liat assay can be performed on-demand and provides physicians with accurate and timely results. One Liat Analyzer can perform up to 24 flu tests in an 8-hour period.
		Easiest. Testing takes 3 simple steps and has a hands-on time of ~1 minute, allowing the test to be performed in hospital near-patient settings. No reagent dispensing, computers or other lab equipment is needed.
		Smartest. The Liat assay’s intelligent features, such as sample volume metering, integrated internal control, and advanced error diagnostics, ensure the quality of results when performed by minimally trained users.
		Reliable results without compromise. Clinical study results show excellent sensitivity and specificity compared to the gold standard viral culture method. Analytical studies further show equivalent or superior performance compared to current influenza nucleic acid tests.

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References

1. CDC Seasonal Influenza Question & Answer. http://www.cdc.gov/flu/about/qa/disease.htm. Accessed July 24, 2011

2. Hurt AC et al. Influenza & Other Respiratory Viruses 2009;3(4):171-76

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Ordering Information

Description	Catalog No.
Liat™ Influenza A/B Assay (20 tests)	40-03778
Exact Volume (EV) Pipettes, 100 μL	40-03794
Liat™ NP Swab Collection Kit	40-03760
Liat™ Influenza A/B QC Kit	40-03759
Liat™ Analyzer	40-03010

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